Side Effects from Medication & Specialty Drugs

Commonly Requested Formulas for Patients with Mouth Sores/Mucositis

  • Stanford Modified Mouthwash (MucoLox™)
  • Misoprostol/Diphenhydramine HCl/Lidocaine HCl Oral Rinse (MucoLox™)
  • Misoprostol/Ketoconazole/Tetracycline HCl/Triamcinolone Acetonide/Chlorpheniramine Maleate/Deoxy-D-Glucose Oral Rinse (MucoLox™)
  • Beta Glucan/Dexpanthenol/Vitamin E Acetat Oral Rinse (MucoLox™)
  • Dexamethasone/Tetracycline HCl/Nystatin/Diphenhydramine HCl Mouthwash (MucoLox™)
  • Stanford Mouthwash (MucoLox™)

Commonly Requested Formulas for Patients with a Headache

  • Sumatriptan/Tramadol HCl/Gabapentin/Doxepin HCl/Indomethacin Topical Lipoderm®
  • Lidocaine HCl Isotonic Nasal Spray
  • Dichloralphenazone/Isometheptene Mucate/Acetaminophen Capsules
  • Ketoprofen/Cyclobenzaprine HC Topical Lipoderm® ActiveMax™ (BUD Study)
  • Indomethacin Topical Lipoderm®
  • Indomethacin Base MBK Suppository (Pink Mold)

Commonly Requested Formulas for Patients with Dizziness, Vomiting, Nausea

  • Lorazepam/Diphenhydramine HCl/Haloperidol/Metoclopramide Topical Lipoderm®
  • Ondansetron Topical Lipoderm ActiveMax®
  • Ondansetron Oral Effervescent
  • Ondansetron Oral Suspension (SuspendIt™)
  • Scopolamine Hydrobromide Topical Lipoderm®
  • Promethazine HCl Topical Lipoderm® (BUD Bracketed Study)
  • Ginger Root Sorbitol Lollipop Base

Commonly Requested Formulas for Patients with Insomnia

  • Melatonin Sublingual Suspension (MucoLox™)
  • Lorazepam Gelatin Troche
  • Lorazepam Topical Lipoderm® (BUD Study)
  • Tryptophan Capsules

Commonly Requested Formulas for Patients with Peripheral Neuropathy

  • Ketamine HCl/Gabapentin/Clonidine HCl/Baclofen Topical Lipoderm® ActiveMax™
  • Ketamine HCl/Gabapentin/Clonidine HCl/Baclofen Topical Lipoderm®

Commonly Requested Formulas for Patients Experiencing Drowsiness

  • Caffeine Sorbitol Lollipop Base
  • Caffeine Citrate Oral Suspension (SuspendIt™)
  • Yohimbine HCl Capsules

Commonly Requested Formulas for Patients with Diarrhea

  • Loperamide HCl Rectal Gel (MucoLox™/VersaBase®)
  • Hyoscyamine Sulfate Base A Troche
  • Hyoscyamine Sulfate Slow Release Capsules
  • Morphine (Anhydrous) Oral Solution
  • Kaolin/Pectin/Belladonna/Paregoric Oral Liquid

Commonly Requested Formulas for Patients with Dry Skin

  • Sodium Hyaluronate Topical Gel
  • Aloe Vera Topical Gel (PracaSil®-Plus)
  • Urea Topical Gel (PracaSil®-Plus)
  • Urea/ Sodium Hyaluronate/PracaSil®‐Plus Topical Gel (Spira‐Wash™)
  • Emu Oil/Panthenol/Bacocalmine™ PH/Dimethyl Sulfone/Sodium Hyaluronate Topical Lotion

Commonly Requested Formulas for Patients with Vaginal Dryness

  • Vitamin E/Vitamin A/Sodium Hyaluronate Vaginal Gel (MucoLox™/VersaBase®)
  • Vitamin E Vaginal Gel (MucoLox™/VersaBase®)

Commonly Requested Formulas for Patients with Increased Sweating

  • Glycopyrrolate Topical Solution
  • Glycopyrolate Topical Lotion
  • Aluminum Chloride Topical Solution

Commonly Requested Formulas for Patients with Dry Mouth

  • Pilocarpine HCl Oral Drops (MucoLox™) (BUD Study)
  • Artificial Saliva Gel (MucoLox™)
  • Pilocarpine HCl Sorbitol Lollipop Base
  • Sodium Chloride/Potassium Chloride/Calcium Chloride Base A Troche
  • Saline/Glycerin Oral Suspension
  • Oral Rinse ‐ General Formula (MucoLox™)
  • Electrolyte Saliva Gel (MucoLox™)
  • Supersaturated Calcium Phosphate Oral Rinse (MucoLox™)

Commonly Requested Formula for Patients with Memory Impairment

  • Selegiline HCl Polyglycol Troche

Commonly Requested Formulas for Patients with a Skin Rash

  • Betamethasone Valerate/Tranilast Topical Gel (PracaSil®-Plus)

Commonly Requested Formulas for Patients with Alopecia

  • Squaric Acid Dibutyl Ester Topical Solution
  • Diphenylcyclopropenone Topical Solution
  • Minoxidil/Tretinoin Topical Gel
  • Minoxidil Topical Solution

Commonly Requested Formulas for Patients with Pruritis

  • Lidocaine HCl/Diphenhydramine HCl/Dexamethasone/Cimetidine Topical Cream (VersaBase®)
  • Hydrocortisone/Pramoxine HCl Topical Cream
  • Pitch Ointment (PracaSi®‐Plus)
  • Diphenhydramine HCl/Pramoxine HCl/Hydrocortisone Acetate Compound Topical Gel

Side Effects of Specialty Drugs

Harvoni

Chronic Hepatitis C genotype 1 in adults

CNS: headache and fatigue

  • Nausea
  • Insomnia
  • Diarrhea
  • Increased serum lipase
  • Hyperbilirubinemia

Olysio

Chronic Hepatitis C genotype 1.

Offlabel: Chronic Hepatitis C genotype 4 and 1 for treatment naïve pts or those who cannot take peninterferon alfa

CNS: fatigue, headache, dizziness, insomnia

Derm: pruritis, skin rash (erythema, eczema, maculopapular rash, urticaria, toxic skin eruption, dermatitis, exfolatiave cutaneous vasculitis, photosensitivity reaction

GI: nausea, diarrhea

Hepatic: increased serum bilirubin

Neuromuscular/skeletal: myalgia

Respiratory: Dyspnea

Skin photosensitivity grade 3, skin rash, increased serum alkaline phosphatase

Sovaldi

Chronic hepatitis C genotype 1, 2, 3, 4 and combination HIV/HCV coinfection.

Offlabel: Chronic hepatitis C genotype 5 & 6 in treatment niave or relapse patients

CNS: chills, fatigue, headache, insomnia, irritablity

Derm: pruritis, skin rash

GI: decreased appetite, diarrhea, nausea

Hematologic/Oncologic: anemia, decreased hemoglobin, decreased neutrophils, neutropenia

Neuromuscular/skeletal: myalgia, weakness.

Respiratory: flu like symptoms,

Misc: fever

GI: increased serum lipase

Hematologic/Oncologic: Thrombocytopenia

Hepatic: Increased serium bilirubin

Neuromuscular/skeletal: increased creatine phosphokinase

<1%: pancytopenia, severe depression, suicide ideation

Pegasys

Chronic Hepatits B & C. Offlabel: Polycythemia vera, renal cell carcinoma, chronic myelogenous leukemia, chronic Hepatitis C genotypes 1, 4, 5 or 6

CNS: anxiety, depression, dizziness, fatigue, fever, headache, insomnia, irritability, pain

Derm: alopecia, pruritis

GI: abdominal pain, anorexia, diarrhea, nausea/vomiting

Hematologic: neutropenia

Musculoskeletal: arthralgia, myalgia, rigors

Misc: injection-site reaction, pain, pyrexia, resistant mechanism disorders

Bacterial infections

CNS: memory impairment, mood alteration.

Derm: dermatitis, dry skin, eczema, increased sweating, rash.

GI: dry mouth, dyspepsia.

Hematologic: anemia, lymphopenia, thrombocytopenia.

Musculoskeletal: back pain.

Respiratory: cough, dyspnea, exertional dyspnea.

Misc: blurred vision, hypothyroidism, weight decrease

Atripla

HIV-1 infection

Abnormal dreams, depression, diarrhea, dizziness, fatigue, headache, hypercholesterolemia, insomnia, nausea, rash

CNS: anxiety

Derm: rash

GI: vomiting

Respiratory: nasopharyngitis, sinusitis, upper respiratory tract infections

Isentress

HIV-1 infection Offlabel: postexposure prophylaxis for occupational exposure to HIV

Endocrine: increased serum glucose

Hepatic: increased serum ALT/AST

CNS: dizziness, fatigue, headache, insomnia

GI: increased serum amylase, increased serum lipase, nausea

Hematologic/oncologic: abnormal ANC, thrombocytopenia

Hepatic: hyperbilirubinemia, increased serum alkaline phosphatase

Neuromuscular/skeletal: increased creatine phosphokinase

Prezista

HIV-1 infection

Endocrine/Metabolic: hypercholesterolemia, increased LDL.

GI: diarrhea, nausea, vomiting

CNS: fatigue, headache

Derm: pruritus, skin rash

Endocrine/Metabolic: diabetes mellitus, hyperglycemia, increased amylase, increased serum triglycerides

GI: abdominal distension, abdominal pain, anorexia, decreased appetite, dyspepsia, increased serum lipase

Hepatic: Increased serum ALT/AST and increased serum alkaline phosphatase

Reyataz

HIV-1 infection

Derm: skin rash

Endocrine/Metabolic: increased amylase,

increased serum cholesterol GI: Nausea, vomiting

Hematologic/Oncologic: neutropenia

Hepatic: increased serum ALT, increased serum bilirubin, jaundice

Neuromuscular/skeletal: increased creatine phosphokinase

Respiratory: cough

Misc: fever

Cardiovascular: first and second degree artrioventricular block, edema

CNS: depression, dizziness, headache, insomnia, peripheral neuropathy Endocrine/metobolic: hyperglycemia, hypoglycemia, increased serum triglycerides

Hematologic/oncologic: decreased hemoglobin, thrombocytopenia.

Hepatic: increaded AST

Neuromuscular/skeletal: limb pain, myagia

Respiratory: nasal congestion, oropharyngeal pain, rhinorrhea, wheezing

Stribild

HIV-1 infection

GI: diarrhea, nausea

Genitourinary: proteinuria

CNS: abnormal dreams, dizziness, drowsiness, fatigue, headache, insomnia Derm: skin rash

Endocrine/metabolic: increased amylase, increased serum cholesterol, incrased serum triglycerrides GI: flatulence

Genitourinary: hematuria

Hepatic: increased serum AST

Neuromuscular/skeletal: bone fracture, increased creatine phosphokinase

Renal: increased serum creatinine

Truvada

Preexposure prophylaxis for sexually acquired HIV-1, Treatment for HIV-1. Offlabel: preexposure prophylaxis for HIV-1 infection for IV drug users and occupational exposure, treatment for antiviral resistant

Hepatitis B or coinfection with HIV

abnormal dreams, depression, diarrhea, dizziness, fatigue, headache, insomnia, nausea, skin rash

GI: vomiting

Respiratory: nasopharygnitis, sinusitis, upper respiratory tract infection

Cimzia

Ankylosing spondylitis, crohn disease, psoriatic arthritis, rheumatoid arthritis

GI: nausea. Infection. Resipiratory: upper respiratory infection.

Cardiovascular: angina pectoris, atrial fibrillation, cardiac arrhythmia, cardiac failure, cerebrovascular accident, hypertension, hypertensive heart disease, ischemic heart disease, myocardial infarction, pericardial infusion, pericarditis, thrombophlebitis, transient ischemic attacks, vasculitis

CNS: anxiety, bipolar mood disorder, fatigue, headache, suicidal tendencies

Derm: alopecia, dermatitis, erythema nodosum, skin rash, uticaria

Endocrine/metabolic: menstrual disease

Genitourinary: nephrotic syndrome, UTI

Hematologic/oncologic: anemia, hemorrhage, hypercoagubility state, leukpenia, lymphadenopathy, pancytopenia, positive ANA titer Hepatic: hepatitis, increased serum transaminases

Immunologic: antibody development

Neuromuscular/skeletal: arthralgia, back pain

Ophthalmic: optic neuritis, retinal hemorrhage, uveitis

Renal: renal failure

Respiratory: bronchitis, cough, nasopharyngitis, pharyngitis, tuberculosis Misc: fever

Enbrel

ankylosing spondylitis, plaque psoriasis, polyarticular juvenile idiopathic arthritis, psoriatic arthritis, rheumatoid arthritis. Offlabel: graft vs host disease, hidradenitis suppurativa, idiopathic thrombocytopenia purpura, nephrotic syndrome, pyoderma gangrenosum, uveitis, wegener granulomatosis

CNS: headache

Derm: skin rash

GI: abdominal pain, diarrhea, vomiting

Hematologic/oncologic: positive ANA titer Immunologic: antibody development

Infection

Local: injection site reaction

Respiratory: respiratory tract infection, rhinitis, upper respiratory tract infection

CNS: dizziness

Derm: pruritis

GI: dyspepsia, nausea

Neuromuscular/skeletal: weakness

Respiratory: cough, pharyngitis, respiratory distress, sinusitis Misc: fever

Humira

Ankylosing spondylitis, crohn disease, juvenile idiopathic arthritis, plaque psoriasis, psoriatic arthritis, rheumatoid arthritis, ulcerative colits. Offlabel: pyoderma gangrenosum, uveitis.

CNS: headache.

Derm: skin rash.

Hematologic/oncologic: positive ANA titer. Immunologic: antibody development. Local: injection site reaction. Neuromuscular/skeletal: increased creatine phosphokinase. Respiratory: sinusitis, upper respiratory tract infection.

Cardiovascular: atrial fibrillation, cardiac arrest, cardiac arrythemia, cardiac failure, chest pain, coronary artery disease, deep vein thrombosis, hypertension, hypertensive encephalopathy, myocardial infarction, palpitations, pericardial effusion, pericarditis, peripheral edema, subdural hematoma, syncope, tachycardia, vascular disease. CNS: confusion, myasthenia, parasthesia

Derm: Alopecia, cellulitis, erysipelas

Endocrine/metabolic: dehydration, hypercholesterolemia, hyperlipidemia, ketosis, mentrual disease, parathyroid disease

GI: abdominal pain, cholecystitis, cholelithiasis, diverticulitis, esophagitis, gastroenteritis, gastrointestinal hemorrhage, nausea, vomiting

Genitourinary: cystitis, hematuria, pelvic pain, urinary tract infection Hematologic/oncologic: adenoma, agranulocytosis, carcinoma, granulocytopenia, luekopenia, malignant lymphoma, malignant melanoma, pancytopenia, paraproteinemia, polycythemia

Hepatic: hepatic necrosis, increased serum alkaline phosphatase

Hypersensitiviy reaction Infection: herpes zoster, sespis, serious infection

Neuromuscular/skeletal: arthralgia, arthritis, arthropathy, back pain, bone fracture, limb pain, multiple sclerosis, muscle cramps, osteonecrosis, septic arthritis, synovitis, systemic lupus erythematosus, tendon disease, tremor Ophthalmic: cataract

Renal: nephrolithiasis, pyelonephritis

Respiratory: asthma, bronchospasm, dyspnea, flu-like symptoms, pleural effusion, pneumonia, respiratory depression, tuberculosis

Misc: abnormal healing, accidental injury, fever, post operative complication (infection)

Simponi

Ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, ulcerative colitis

Hematolgic/oncologic: Positive ANA titer Infection

Respiratory: upper respiratory tract infection

Cardiovascular: hypertension

CNS: dizziness, parathesia

Derm: skin rash

GI: constipation

Hematologic/oncologic: leukopenia

Hepatic: Increased AST/ALT

Immunologic: antibody development

Infection: bacterial infection, fungal infection, serious infection, viral infection Local: injection site reaction

Respiratory: bronchitis, sinusitis

Misc: fever, infusion related reaction

Stelara

Plaque psoriasis, psoriatic arthritis

Infection

CNS: depression, dizziness, fatigue, headache

Derm: pruritus

GI: nausea

Immunlogic: antibody development

Infection: severe infection

Local: erythema at injection site

Neuromuscular/skeletal: arthralgia, back pain Respiratory: pharyngolaryngeal pain